10.80001/3QHA
Joanna Wysocka
Joanna
Wysocka
Licia Selleri
Licia
Selleri
Tomasz Swigut
Tomasz
Swigut
Activity of chimp neural crest enhancer near COL13A1 in E11.5 transgenic mouse embryo – Tg(panTro4_chr10: 68198369-68199194::LacZ).
Tg(panTro4_chr10: 68198369- 68199194::LacZ) chimp neural crest enhancer with activity in the forebrain, midbrain, hindbrain, trigeminal (V) ganglion, and midgut. This enhancer lacks the expression in the frontonasal process, optic cup, branchial arches, heart field, limb buds, and somites that is observed with the equivalent human enhancer, demonstrating a human species-specific bias when comparing these two species.
FaceBase (www.facebase.org)
2020
Enhancer activity detection by reporter gene assay
Dataset
Craniofacial development
Craniosafial malformation
en
Dataset
1
National Institute of Health (NIH)
5U01DE024449
FaceBase Coordinating Center